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Access to comprehensive services for girls in the East Southern African (ESA) region is slow, and still not integrated into established adolescent health evidence or services. Furthermore, HIV is not effectively incorporated into broader sexual and reproductive health rights (SRHR). Youth voices and involvement is central to designing interventions which will meet the SRHR needs of Africa's youthful population. SAT aims to bolster youth-driven efforts to address social, political, economic factors that increase vulnerability to HIV and support a powerful cadre of adolescent girls and young women (AGYW) to strengthen advocacy prevention efforts. This interactive session will be led by diverse voices of Young Leaders and offer a much-needed youth perspective to engaging with multiple stakeholders on supporting AGYW in the region to enhance their leadership; construct an evidence-based, focused, advocacy agenda aligned to the prevention road-map and adolescent health evidence; develop an AGYW-driven health database, and innovate prevention components.