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Tremendous gains have been made in reducing mother-to-child HIV transmission globally, and many children are now starting life free of HIV. However, much remains to be done to achieve the ambitious goal of ending new HIV infections among children. The Start Free Stay Free AIDS Free, launched by PEPFAR and UNAIDS in 2016 adopted a superfast track agenda to meeting the remaining gaps, to change the trajectory of the epidemic in children once and for all. The session will build consensus on the key strategies that need to be adopted to get us to the ‘last mile’ by addressing the following key issues: 1) Where are we now and what still needs to be done? 2) What are the game changers, innovations and keys to success we can learn from? 3) How can data drive quality and better outcomes for mothers and children?